From: Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
 | Rat Aging* | Human Disease†| ||||
---|---|---|---|---|---|---|
 | 3 mo | 19 mo | 30 mo | Normal | NPH | AD |
CSF Formation Rate (ml/min) | 0.00121 | 0.00148 | 0.00065 | 0.40 | 0.25 | 0.20 |
CSF Volume (space) (ml) | 0.156 | 0.196 | 0.308 | 150 | 300 | 250 |
CSF Turnover Rate (volumes/day) | 11 | 10.8 | 3.0 | 4 | 1.2 | 1.2 |